Technical Project Manager at Nautilus Biotechnology in San Carlos
- Company: Nautilus Biotechnology
- Location: San Carlos
- Job type: full time
- Workplace: onsite
- Posted: 2026-10-23
All open roles at Nautilus Biotechnology
Job description
At Nautilus, we have a big and important mission: to improve the health of millions by unleashing the potential of the proteome to accelerate drug development and enable a new world of precision and personalized medicine. We are developing a single-molecule protein analysis platform of unprecedented sensitivity, scale, and ease of use that we believe will democratize access to the proteome – one of the most dynamic and valuable sources of biological insight. To accomplish this, we are pursuing hard scientific problems with an entrepreneurial mindset and creating a world-class team of builders, innovators, and dreamers across a wide range of disciplines. We are hiring a Technical Project Manager to join our growing team. This position is a critical part of successfully delivering a comprehensive proteomics platform to our customers. The position is responsible for managing multiple projects varying in size and complexity for the development of the Nautilus platform. This role entails working closely with multiple cross-functional teams in R&D, along with Product Management and Manufacturing. The position interfaces with R&D leadership and scientists and is responsible for developing and managing product development schedules from early phases through V&V and internal launch. This role collaborates with teams to plan and track project work, identify risks and resolve issues, and manage deliverables in a dynamic environment. Additionally, this role includes coordinating large, department-wide meetings and communication. The position requires a skilled team leader who pays excellent attention to details, has good experience managing cross functional projects, and who is comfortable getting into the technical details while engaging with the diverse team members and leading them towards a launch-ready product. The project manager will be a leader who can align the goals and deliverables across the organization. The individual will be expected to work independently, with minimal supervision, in developing strategies, detailed project goals and plans, and communicating effectively with all levels of the organization. This person should be able to weigh schedule, scope, and cost decisions and make the case for the tradeoff credibly to R&D and program leadership. Responsibilities & Expectations • Lead medium to large scale projects for the development of the Nautilus platform including; new assays, consumables, software, and hardware. Ability to manage multiple projects simultaneously while understanding their dependencies. • Define project scope, objectives, and quarterly goals in alignment with high-level company and program goals. Measure and report project status using standard project management dashboards, tools, and techniques • Develop project plans, milestones, and deliverables from initial product conception to product release. Experience in synthesizing a diverse set of ideas into a cohesive plan that team leads will own. • Create and manage detailed project schedules. Work with team leads to adopt schedule management strategies. • Collaborate with technical leads and subject matter experts to translate technical risks and experimental outlines into actionable plans with measurable metrics. Help connect technical areas and dependencies between teams. • Identify and mitigate project risks and issues to remove obstacles and ensure milestone delivery on tight timelines. • Facilitate prioritization and tradeoff decisions with teams and stakeholders. Frame tradeoffs in terms of program impact and schedule so leadership can decide quickly and with confidence. • Effectively communicate and present project status to senior management and stakeholders. • Aid in identifying key technical resource gaps; work with functional managers to address resourcing issues. • Utilize common Project Management tools and techniques (such as Smartsheets, Jira, and Excel) to develop appropriate processes with teams. • Prepare agendas, lead meetings, an
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