Senior Project Manager at Iovance Biotherapeutics in Philadelphia, PA
- Company: Iovance Biotherapeutics
- Location: Philadelphia, PA
- Job type: full time
- Workplace: onsite
- Posted: 2026-10-09
All open roles at Iovance Biotherapeutics
Job description
About Iovance Biotherapeutics, Inc. Iovance Biotherapeutics , Inc. is the global leader in innovating, developing, and delivering tumor infiltrating lymphocyte (TIL) cell therapies for patients with solid tumors. Amtagvi® (lifileucel) is the first FDA-approved, one-time treatment for previously treated advanced melanoma, now approved in three global markets and available at more than 95 authorized treatment centers. The Iovance TIL platform spans registrational trials and next-generation programs in additional solid tumors, including gene-edited and IL-12 tethered TIL therapies, next-generation IL-2, and precision immuno-oncology approaches. As the first and only company to take TIL therapy from concept to a broadly accessible commercial treatment, Iovance operates as an end-to-end cell therapy company, anchored by fully owned, centralized U.S.-based manufacturing that is scaled to serve thousands of cancer patients worldwide each year. For more information, please visit www.iovance.com . Amtagvi® and its accompanying design marks, Proleukin ® , Iovance ® , and IovanceCares™ are trademarks and registered trademarks of Iovance Biotherapeutics, Inc. or its subsidiaries. All other trademarks and registered trademarks are the property of their respective owners. Information on Iovance’s broad, industry-leading patent portfolio is available on the Intellectual Property page on www.iovance.com . Overview The Senior Project Manager will play a key role in the development, management, and execution of Iovance’s manufacturing sites’ project portfolios in Philadelphia, PA, reporting to the Senior Director, Operational Excellence. This experienced individual will shape project management processes and standards and provide guidance to less experienced project managers. The role will be responsible for planning, leading, and managing the successful execution of complex cross-functional projects aligned with site and company objectives and priorities. This role will also be responsible for establishing and reporting on key portfolio and project metrics in support of on time and within budget project deliverables. As a member of the Operational Excellence department, this individual will act as a change agent to instill a culture of continuous improvement and support building capabilities to enable individuals and teams to identify opportunities for improvement and independently implement solutions. Essential Functions and Responsibilities Shape project management processes and standards and provide guidance to less experienced project managers. Engage with senior leaders, sponsors, and stakeholders to ensure alignment of projects with organizational strategy. Identify and mitigate risks at a portfolio level and develop strategies for risk management that affect multiple projects or the organization. In collaboration with cross-functional teams, create, establish, and maintain integrated project plans. Lead and facilitate complex cross-functional projects with minimal oversight through all life cycle phases: initiation and feasibility, planning and design, execution, and closing. Deliver timely, high-quality output on multiple projects simultaneously by utilizing project management skills including clear project charters, timeline and budget management, data collection and analysis, and communication plans. Utilize escalation plans and countermeasures when outcomes, timelines, or budgets are at risk. Identify interdependencies, critical path and at-risk activities, anticipate bottlenecks, and help remove barriers to progress against department or corporate goals. Establish, monitor, and report on portfolio and project progress to senior leadership utilizing status / dashboard reports. Act as a subject matter expert coaching all levels of the organization in project management concepts, best practices, and tool application to increase the capability of the business. Build productive internal and external working relationships with stakeholde
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