Senior Director, Pipeline Commercial Strategy at Iovance Biotherapeutics

Job description

About Iovance Biotherapeutics, Inc. Iovance Biotherapeutics , Inc. is the global leader in innovating, developing, and delivering tumor infiltrating lymphocyte (TIL) cell therapies for patients with solid tumors. Amtagvi® (lifileucel) is the first FDA-approved, one-time treatment for previously treated advanced melanoma, now approved in three global markets and available at more than 95 authorized treatment centers. The Iovance TIL platform spans registrational trials and next-generation programs in additional solid tumors, including gene-edited and IL-12 tethered TIL therapies, next-generation IL-2, and precision immuno-oncology approaches. As the first and only company to take TIL therapy from concept to a broadly accessible commercial treatment, Iovance operates as an end-to-end cell therapy company, anchored by fully owned, centralized U.S.-based manufacturing that is scaled to serve thousands of cancer patients worldwide each year. For more information, please visit www.iovance.com . Amtagvi® and its accompanying design marks, Proleukin ® , Iovance ® , and IovanceCares™ are trademarks and registered trademarks of Iovance Biotherapeutics, Inc. or its subsidiaries. All other trademarks and registered trademarks are the property of their respective owners. Information on Iovance’s broad, industry-leading patent portfolio is available on the Intellectual Property page on www.iovance.com . Overview The Sr. Director, Pipeline Commercial Strategy will own the commercial assessment of Iovance's pipeline assets, including market sizing, target product profiles and competitive analysis. This role brings deep commercial domain expertise to quantify market opportunities, shape portfolio and indication strategy, and ensure disciplined execution of priority workstreams from early, upstream pipeline development. This commercial subject matter expert will proactively identify what needs to be done, define the path forward, and drive the organization to execute. Essential Functions and Responsibilities Senior commercial strategy role owning the commercial assessment of pipeline assets and indication expansions including market sizing and addressable market analysis, target product profiles (TPPs), competitive analysis, and representing reimbursement market analysis from early development through launch Defines and drives actionable commercial strategies, workplans, timelines, and readiness deliverables grounded in deep knowledge of oncology markets, treatment paradigms, and cell therapy commercialization Represents Commercial in established enterprise forums such as PDT and GDT, operating as the strategic integrator who drives alignment through expertise New Product Planning & Portfolio Strategy Build market sizing and addressable market analyses by tumor type, line of therapy, and geography, using epidemiology, treatment-flow, and claims data to quantify the commercial opportunity Develop and maintain commercially grounded target product profiles (TPPs) for pipeline assets, defining the efficacy, safety, dosing, and differentiation thresholds needed to compete in each target indication Own competitive analysis and scenario planning for pipeline indications, tracking competitor programs, data readouts, and approvals, modeling competitive entry, label variation, treatment landscape shifts, and outpatient usage opportunities, and defining the differentiation strategy for Iovance assets Drive portfolio prioritization, forecasting, and commercial recommendations to inform Go/No-Go decisions for registrational trials Lead early commercial assessments for pipeline assets, indication expansions, in-licensing opportunities, acquisitions, and business development evaluations, applying deep market knowledge to shape investment decisions Provide commercial input on tumor target, indication, and launch market selection, including signal-finding studies and investigator-sponsored trials (ISTs) that support future registrational trials Partner with Cli