Senior Director, Head of Oncology at Jazz Pharmaceuticals in Home-Based

  • Company: Jazz Pharmaceuticals
  • Location: US - Home-Based
  • Salary: $228K – $342K
  • Job type: full time
  • Workplace: remote
  • Posted: 2026-10-28

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Job description

If you are a current Jazz employee please apply via the Internal Career site Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit www.jazzpharmaceuticals.com for more information. Job Description Brief Description: The Senior Director, Head of Oncology Project Management provides strategic operational leadership, coaching, and portfolio-level oversight for the oncology project management organization at Jazz Pharmaceuticals. This leader focuses on fostering, equipping, and scaling a high-performing team of Project Managers. The oncology PM team is responsible for driving global oncology programs through the full development lifecycle. This role ensures that the Oncology PM team has tools, strategic mindset, and talent density to drive critical-path execution and operational excellence. The Senior Director partners closely with Oncology Therapeutic Area Leadership to operationalize portfolio strategy and proactively manages team capacity. Essential Functions People Leadership & Coaching Team Leadership: Direct, mentor, and foster an elite oncology project management team capable of driving programs across Phase 1, late-stage, regulatory filing, and global launch. Capability Building: Coach and develop PMs to proactively identify critical path dependencies, manage cross-functional execution, and maintain rigorous operational standards. Establish PMs as the strategic operational leaders (“COOs of their projects”) co-leading Development Teams/Global Project Teams (GPTs) in tandem with Early/Late Development Leads. Talent Development: Implement individualized development plans, succession planning, and proactive recruitment to ensure critical programs are staffed with top-tier talent. Prevent burnout and optimize workload distribution through active capacity management. 2. Portfolio Oversight & Execution Excellence Milestone Tracking: Maintain high-level line-of-sight on all oncology program health, key milestones, critical paths, and project risk profiles. Operational Excellence: Partner with Oncology Therapeutic Area Leadership to convert clinical development plans into integrated operational roadmaps, ensuring that pipeline assets advance through the development continuum with speed and quality. Gap Coverage: Actively step in to directly manage a project or program when necessary to bridge a critical team resource or staffing gap. 3. Governance & Decision Framing Strategic Governance: Guide and support PMs as they prepare their project teams for governance committees, ensuring rigorous preparation and data-driven pre-reads. Trade-Off Analysis: Help team frame complex decisions for executive leadership through clear trade-off analyses balancing timelines, cost, resources, and risk. Risk & Issue Management: Facilitate proactive risk identification, mitigation plans, and contingency execution across all programs. 4. Resource, Capacity & Budget Management Capacity Planning: Proactively forecast FTE resource bottlenecks and partner with functional heads to resolve gaps partnering with the Resource Management Team. Financial Management: Maintain oversight of oncology program budgets, collaborating with Finance to track variances, commitments, and multi-million-dollar program allocatio

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