Production Planner at Iovance Biotherapeutics in Philadelphia, PA

Job description

About Iovance Biotherapeutics, Inc. Iovance Biotherapeutics , Inc. is the global leader in innovating, developing, and delivering tumor infiltrating lymphocyte (TIL) cell therapies for patients with solid tumors. Amtagvi® (lifileucel) is the first FDA-approved, one-time treatment for previously treated advanced melanoma, now approved in three global markets and available at more than 95 authorized treatment centers. The Iovance TIL platform spans registrational trials and next-generation programs in additional solid tumors, including gene-edited and IL-12 tethered TIL therapies, next-generation IL-2, and precision immuno-oncology approaches. As the first and only company to take TIL therapy from concept to a broadly accessible commercial treatment, Iovance operates as an end-to-end cell therapy company, anchored by fully owned, centralized U.S.-based manufacturing that is scaled to serve thousands of cancer patients worldwide each year. For more information, please visit www.iovance.com . Amtagvi® and its accompanying design marks, Proleukin ® , Iovance ® , and IovanceCares™ are trademarks and registered trademarks of Iovance Biotherapeutics, Inc. or its subsidiaries. All other trademarks and registered trademarks are the property of their respective owners. Information on Iovance’s broad, industry-leading patent portfolio is available on the Intellectual Property page on www.iovance.com . Overview The Production Planner is the owner and responsible for managing and scheduling production plans for sampling, testing, issuance, bulk manufacturing, and final product shipments at Iovance Cell Therapy Center (iCTC) located in Navy Yard, PA and third-party manufacturing contractors as required. The Production Planner is key communication link between Manufacturing, Materials, Quality, Logistics, Maintenance, MSAT, Commercial, Clinical, and other teams to address additions, changes, substitutions, etc. in the schedule and ensure it is balanced, consistent with Iovance objectives, and meets patient needs. The Production Planner will follow business rules that govern lead times, incubation times, and other planning parameters. The Production Planner will ensure all plants within the manufacturing network execute to the approved production plan through the facilitation of forecasting and supply meetings. Essential Functions and Responsibilities Develop, establish, and maintain the site Production Schedule for the defined planning horizon, including production date, shift, production sequence, and manufacturing room assignments. Optimize the schedule based on cleaning requirements, incubation windows, material storage and staging requirements, workforce availability, equipment capacity, room availability, and other operational constraints to maximize manufacturing throughput, schedule adherence, and batch success. Develop, publish, and maintain integrated weekly Warehouse, Production, and Maintenance schedules to support execution of S&OP-approved production volumes and patient demand. Incorporate known constraints related to material availability, trained resources, equipment, facility capacity, maintenance activities, quality requirements, and other dependencies that may impact production execution or final product delivery. Serve as the primary point of contact for the near-term Production Schedule, typically covering the next two weeks, coordinating with Manufacturing, Buyer/Planning, Logistics, Facilities, Warehouse, Quality Control, IT, and other impacted functions. Facilitate timely resolution of scheduling conflicts and make informed scheduling decisions within the scope of the role, prioritizing patient impact, product delivery, safety, quality, compliance, and overall site objectives. Monitor and evaluate production plan execution against actual performance on a routine basis. Maintain accurate planning and scheduling systems and tracking mechanisms to provide visibility to the status and progression of production orders, mater