Medical Director, Clinical Development (Oncology) at Allogene Therapeutics in San Francisco, CA

Job description

About Allogene: Allogene Therapeutics, with headquarters in South San Francisco, is a clinical-stage biotechnology company pioneering the development of allogeneic chimeric antigen receptor T cell (AlloCAR T) products for cancer and autoimmune disease. Led by a management team with significant experience in cell therapy, Allogene is developing a pipeline of “off-the-shelf” CAR T cell product candidates with the goal of delivering readily available cell therapy on-demand, more reliably, and at greater scale to more patients. About the role: The Medical Director will lead the execution of an oncology clinical program with activities and accountability spanning medical leadership/monitoring of an active trial as well as developing and driving the clinical development strategy in alignment with the overall portfolio strategy of Allogene. This role is based out of Allogene’s headquarters in South San Francisco, CA. Remote candidates will be evaluated based on suitability for the position along with frequent to travel to Allogene’s South San Francisco or Los Angeles office. Responsibilities include, but are not limited to: Medical monitoring and study leadership role of one or more clinical trial in oncology that may range from pre-IND through late development and registration Seamless, productive integration into a multidisciplinary team across all departments involved in the design, execution, analysis and reporting of clinical trials Facility with the subject matter of clinical development-adjacent functions including clinical operations, translational science, regulatory affairs, drug safety, biostatistics Collaborate with functional leaders to set strategy and shared objectives and interactions with health agencies and vendors (including CROs) Act as a point of contact and project representative to governance and other decision-making bodies, including information dissemination and the resolution of critical project issues Define clinical study protocols; recommend new clinical trial sites and investigators; recommend specific data outputs and publications Apply scientific knowledge, clinical knowledge and extensive drug development experience to ensure the research and development strategies can address critical patient needs by improving the current standard of care for target oncology indications Contribute to the design, start-up, execution, analysis and communication of the clinical studies for a product candidate Interface with internal and external scientists, clinicians and stakeholders to assure the swift identification of new development opportunities and to continuously optimize and refine the development strategy Establish cross-functional relationships with leaders from key cross-functional lines including Regulatory Affairs, Clinical Operations, Commercial, Program Management, etc. and leverage those relationships to manage key project issues including but not limited to Research, Development, Commercial, Manufacturing and Competitive Intelligence Contribute relevant trial information to pipeline and prioritization analyses Ensure that projects are managed appropriately per budget and that the necessary resources are available to the projects to support their success Represent Allogene at meetings with regulatory authorities and third parties such as licensing or co-development partners, consultants, etc. Other duties as assigned Position Requirements & Experience: Medical Degree, residency and fellowship completed in oncology with at least 5 years of relevant post graduate experience in the biotech, pharmaceutical, academic and/or medical research environment (industry experience preferred) Experience in hematology or oncology required (experience in cell therapy highly preferred) Demonstrate a dedication to the mission of Allogene: to work hard to deliver life-saving new medicines for patients with cancer Exemplify a positive, can-do attitude and work independently, often across functional lines, to move the pro