Expert Science & Technology – Downstream Process Development (m/f/d) - Razvoj procesov izolacije in čiščenja bioloških učinkovin (m/ž/d) at Novartis in Mengeš

Job description

Salary Range: €27,160.00 - €50,440.00 Job Description Summary At Novartis, we are reimagining medicine by transforming breakthrough science into life-changing therapies for patients worldwide. We are the Downstream Development team focused on the early-phase development of biopharmaceutical drug substances, leveraging advanced technologies, science-based approaches, and digital solutions to design and optimize processes for manufacturing scale, contributing to the delivery of high-quality, safe, and effective medicines. Role Purpose As an Expert in our Downstream Process Development team in Mengeš, you will contribute scientific and technical expertise to the development of robust, scalable purification processes for next-generation biologics. Combining hands-on DSP knowledge with modelling, digitalization and AI-enabled approaches, you will work with cross-functional teams to plan and execute development studies, interpret results and support sound scientific decisions across development programs. V Novartisu na novo osmišljamo medicino s preoblikovanjem vrhunske znanosti v terapije, ki spreminjajo življenja bolnikov po vsem svetu. Smo ekipa za razvoj procesov izolacije in čiščenja, osredotočena na zgodnje faze razvoja bioloških učinkovin. Z uporabo naprednih tehnologij, znanstveno utemeljenih pristopov in digitalnih rešitev načrtujemo ter optimiziramo procese za proizvodno merilo in tako prispevamo k zagotavljanju visokokakovostnih, varnih in učinkovitih zdravil. Kot Expert v laboratorijskem razvoju procesov izolacije in čiščenja bioloških učinkovin boste s svojim znanstvenim in tehničnim znanjem prispevali k razvoju robustnih in skalabilnih procesov čiščenja za biološka zdravila nove generacije. Praktično znanje DSP boste povezovali z modeliranjem, digitalizacijo in pristopi umetne inteligence ter v sodelovanju z medfunkcijskimi ekipami načrtovali in izvajali razvojne študije, interpretirali rezultate in podpirali znanstveno utemeljeno odločanje. Location: Mengeš, Slovenia LI#hybrid Job Description In this role, you will: Contribute to downstream process development activities across assigned projects, coordinating own tasks and supporting high-quality delivery within agreed timelines and project requirements. Design, plan, execute and document laboratory studies for the development and optimization of robust purification processes for recombinant proteins, with guidance for more complex activities and applying a right-first-time approach. Perform and optimize DSP processes and methods, and evaluate opportunities to implement new technologies. Manage, analyze and interpret experimental data; draw scientifically sound conclusions, propose follow-up studies, and contribute to troubleshooting process challenges. Prepare high-quality protocols, technical reports, laboratory procedures, SOPs, development documentation, handover packages and regulatory-relevant deliverables. Represent DSP in local and global cross-functional project teams, providing scientific input and evidence-based recommendations within the assigned area of responsibility. Support process scale-up, technology transfer and implementation at internal or external manufacturing sites, including knowledge transfer and definition of process controls. Advance DSP capabilities through automation, process modelling, digitalization, data science and AI-enabled development approaches. Communicate scientific results, achievements, risks and recommendations effectively to project teams, stakeholders and external partners, and contribute to publications, patents and scientific conferences, as appropriate. Share knowledge with colleagues, support laboratory organization and DSP equipment activities, and ensure compliance with applicable quality, ethics, health, safety, environmental and information-security requirements. Education & Technical expertise PhD in Biotechnology, Biochemical or Chemical Engineering, Biochemistry, Biology, Pharmaceutical Technology or a related sc