Drug Substance Production Supervisor at GSK in Marietta, PA

Job description

Business Introduction: We manufacture and supply reliable, high-quality medicines and vaccines to meet patients’ needs and drive our performance. Our network of 37 medicines and vaccines manufacturing sites delivered 1.7 billion packs of medicines and 409 million vaccine doses in 2024 to help make a positive impact on the health of millions of people. Our supply chain is not just core to our operations; it’s vital to bringing our innovations to patients as quickly, efficiently and effectively as possible. Technology is transforming how we manufacture medicines and vaccines, enabling us to increase the speed, quality and supply. We need the very best minds and capability to help us on our journey to make more complex products, harnessing the power of smart manufacturing technologies including robotics, digital solutions and artificial intelligence to deliver for patients. Position Summary: You will lead day-to-day manufacturing operations in the Drug Substance (DS) area and be responsible for the timely, cost-effective, safe, compliant, and reliable delivery of a Drug Substance to customers. Supervise a team to ensure that safety, quality, compliance, and delivery targets for commercial product manufacturing are achieved. This role is responsible for making sure that all manufacturing operations are executed in a cGMP-compliant manner and in alignment with company standards. You will manage staff training and qualifications so operating procedures are consistently followed. Develop, supervise, lead, and motivate a multi-disciplinary team. As a member of the Manufacturing leadership team, contribute to departmental and site objectives while maintaining a strong customer focus. You will guide a team of technicians to deliver safe, compliant, and reliable production. You will work closely with Quality, Engineering, Planning, and Supply teams. We value clear communication, practical problem solving, and a focus on continuous improvement. This role offers growth, real impact on supply, and alignment with GSK’s mission of uniting science, technology and talent to get ahead of disease together. Key Responsibilities: Ensure Process Safety, EHS and Regulatory Compliance. Be accountable for area EHS performance, promote a strong safety culture, and help sustain machinery safety management processes and procedures. Identify, report, and remove safety risks. Ensure activities are executed in accordance with quality and regulatory standards. Promote a quality mindset and quality excellence in all activities. Implement and monitor quality systems to maintain inspection readiness, support effective risk management, participate in deviation investigations, and ensure compliance with applicable GSK Quality Management System policies, procedures, and Data Integrity ALCOA+ principles. Assist with production planning to achieve departmental and site objectives. Deploy the performance management process within the area, using accurate and timely data to set, monitor, and achieve objectives, metrics, and targets. Work with other Supervisors to establish, monitor, and achieve annual manufacturing and delivery plans. Ensure relevant production information and activities are tracked, captured, completed, and communicated to management as needed. This includes managing discretionary spend, coordinating with Technical Services to ensure preventive and predictive maintenance and calibrations are appropriate and completed on schedule, and supporting coordination between Manufacturing and QC for environmental monitoring and production processes. Drive and embed the use of GSK Production System (GPS) tools and techniques to realize ever increasing levels of value from manufacturing operations. Must be an effective communicator, focus team by prioritizing what matters most and using data to drive decision making and develop self and team. Support and develop team members through coaching and mentoring. Assign meaningful projects and challenging responsibiliti