Director, US Commercial Risk Evaluation and Mitigation Strategies (REMS) Lead at Agios Pharmaceuticals in CAMBRIDGE, MA

Job description

Director, US Commercial Risk Evaluation and Mitigation Strategies (REMS) Lead Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built. To learn more, visit www.agios.com and follow Agios on LinkedIn and X . The impact you will make: The Director, US Commercial REMS Lead drives US Commercial strategies, activities, and insight gathering related to REMS (Risk Evaluation and Mitigation Strategies). The Director leads the development, implementation, and ongoing management of commercial related REMS activities to support compliance, patient safety, and effective execution across sales, field marketing, patient support, specialty distribution and other customer-facing teams. This role requires partnership with Commercial, Safety, Regulatory, Patient Services, and external vendors to translate REMS requirements into clear strategies, aligned tactics, and measurable outcomes. What you will do: Serve as the primary Commercial liaison on REMS topics across internal stakeholders and external partners. Attend select Governance and REMS core team meetings. Lead US Commercial strategy, operations, and insight generation across Agios products/indications with a REMS. Partner with Sales, Marketing, Commercial Training, Patient Services, Safety, Quality Assurance and Regulatory teams to align strategy, communications, and execution. Lead the Commercial implementation of new REMS programs/modifications and ongoing compliance activities. Participate in cross-functional workstreams to implement initiatives that improve REMS effectiveness and ensure ongoing success of the program. Support the development of Commercial REMS training, communication, and materials that enable effective REMS understanding and pull-through. Use multiple data sources to generate Commercial insights, refine strategy, and strengthen operational performance. Partner with Commercial Operations and Analytics to design, track, and present key commercial REMS related metrics and KPIs to leadership. Foster strong collaboration and accountability across internal teams and external partners. What you bring: Bachelor’s degree in a scientific or business discipline. 10+ years of experience in biotechnology or a related industry. Demonstrated REMS experience within a Commercial environment. Strong record of high performance in operational and cross-functional roles. Experience leading large, complex, cross-functional initiatives. Excellent communication skills and the ability to build strong partnerships. Strong understanding of compliance requirements and guidance governing REMS programs. High learning agility, sound judgment, and strong people skills. Experience leading people, projects, or both. MBA or other advanced degree preferred. Experience in rare disease preferred. Concerned that you don’t check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other’s differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you’re excited about this role but your previous experience doesn’t align perfectly with the job description, we still encourage you to apply. You may be