Director, Enterprise Architecture - Research and Development at Gilead in Foster City, CA

  • Company: Gilead
  • Location: United States - California - Foster City
  • Salary: $226K – $293K
  • Job type: full time
  • Workplace: onsite
  • Posted: 2026-10-13

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Job description

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description The Director, Enterprise Architecture, Research & Development is an individual contributor and strategic architecture leader responsible for shaping the technology direction for Gilead R&D. Operating in a centralized, federated model, this role partners with scientific and business leaders, domain and solution architects, data and digital teams, security, infrastructure, quality, compliance, product and delivery organizations. The Director serves as a trusted advisor and architecture lead for initiatives of varying size and complexity across R&D. The role translates current and anticipated scientific and business needs into capability models, target-state architectures, transition plans, investment recommendations and multi-year roadmaps. The Director guides architecture decisions through established governance and ensures solutions are secure, scalable, interoperable, compliant, financially sound and fit for scientific purpose. Reporting into the Senior Director, Enterprise Architecture Lead, this position is a critical role in our centralized Enterprise Architecture team, and a key leader for our Architecture Community of Practice. This position is based in our global headquarters in Foster City, CA. Job Responsibilities • Shape and evolve R&D technology strategy and multi-year roadmaps, aligning scientific priorities and future capability needs with enterprise architecture standards and technology strategy. • Lead architecture for initiatives of varying size and complexity that enable larger R&D functions or multiple functions to achieve their objectives, connecting business, information, application, integration, data, platform, security and technology domains. • Develop capability models, current-state and target-state architectures, reference architectures, transition architectures, reusable patterns and implementation guardrails that guide delivery and long-term evolution. • Define architecture strategy for scientific AI and knowledge capabilities, including foundation and domain-specific models, model adaptation, retrieval architectures, knowledge graphs, ontologies, semantic layers, scientific agents and AI-enabled workflows. • Evaluate build, buy, reuse, integrate, modernize, consolidate and retire options. Develop recommendations that balance business value, total cost of ownership, risk, technical debt, interoperability, resource needs and long-term maintainability. • Lead architecture reviews through established governance forums. Clearly document and communicate options, trade-offs, decisions, risks, exceptions, dependencies and remediation actions in business and technical terms. • Provide architecture guidance across the solution lifecycle, including use-case analysis, prototyping, blueprinting, design, integration, testing, validation, deployment, operational readiness and

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